Looping Network Meetings

#37 January 27, 2023

Monday, 15:00 CET

Aimee Torres

Model of the human liver circulatory system

Abstract:
The liver is the largest organ within the body. It performs many important functions such as food digestion, energy storage and toxin removal. To perform these functions, the liver has a peculiar circulatory system composed of two blood supply vascular networks, the microcirculation, and the drainage vascular network. The understanding of hemodynamics and hepatic vasculature is fundamental to study the affectations that liver diseases cause on them. We develop a model of the entire human liver circulatory system, from macrocirculation to microcirculation. We use physiological values on the dimensions and hemodynamics of the hepatic vascular system as model inputs, and we obtain results within the physiological range as well. We are able to obtain the blood flow and pressure at different key points of the vasculature. We emulate some liver vascular alterations and successfully reproduce their affectation on the hemodynamics, obtaining results according to those clinically observed.

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